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Clinical Trials

As part of an academic medical center, the Department of Preventive Medicine aims to improve the human health through scientific research, and clinical trials play a major role. Clinical trials test or study drugs, surgical procedures, medical devices or interventions with human subjects. They look to determine their safety and effectiveness in relation to treating specific diseases. 

Browse our active clinical trials below, and visit the Clinical Trials Frequently Asked Questions page for more information.

Trials

NIH All of Us Research Program Precision Medicine Initiative® Precision Medicine Initiative Cohort Program Healthcare Provider Organization Enrollment Centers

Research Program in Illinois. The mission of this ambitious National Institutes of Health (NIH) initiative is to speed up health research and medical breakthroughs. To do this, the All of Us Research Program is asking one million people to lead the way to provide the types of information that can help us create individualized prevention, treatment, and care for all of us. Visit nm.org/joinallofus to learn more and enroll.

WHATARE THE BENEFITS OF JOINING?

· · ·

WHATWOULD I NEED TO DO?

· · · Visit an All of Us Participant Center for physical measurements (bloodpressure, height, weight, waist/hip, & heart rate) and biosamples (blood& urine)

Participants receive a $25 payment for completing all researchcomponents.You will also receive a voucher for free parking.

Eligibility Criteria- 18 years of age or older- Currently live in the United States
Principal InvestigatorHo, JoyceHo, Joyce
Location(s)
  • Map it 201 E. Huron St.
    Chicago, IL
IRB number STU00204480
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Evaluating the EVO treatment optimized for resource constraints

EVO is a 12-month healthy lifestyle and weight loss research study taking place in the Department of Preventive Medicine at Northwestern University. Researchers are looking to determine the best strategy for weight loss and healthy living. Participants enroll in the 12-month study and receive a free 6-month …
EVO is a 12-month healthy lifestyle and weight loss research study taking place in the Department of Preventive Medicine at Northwestern University. Researchers are looking to determine the best strategy for weight loss and healthy living. Participants enroll in the 12-month study and receive a free 6-month health program.

Eligibility CriteriaYou are between the ages of 18 - 70 years old. You are NOT currently pregnant, trying to become pregnant, or breastfeeding.You do NOT have an unstable medical condition.You own an Android or iPhone smartphone.You are willing to track your lifestyle behaviors for 6 months, and attend remote sessions with study staff over the course of 12 months.
Principal InvestigatorPfammatter, Angela FidlerPfammatter, Angela Fidler
Location(s)
  • Map it 680 N. Lake Shore Drive Suite 1410
    Chicago, IL
ClinicalTrials.gov IdentifierNCT04708769IRB number STU00212742
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OPT2MOVE

About the StudyOpt2Move is a 6-month smartphone-based study to help adolescent and young adult cancer survivors become more active.What’s involved? AssessmentsComplete before starting study and at 3 and 6 months: 45-min online surveyWear activity monitor 24/7 for 7 days You will be compensated for …

About the Study

Opt2Move is a 6-month smartphone-based study to help adolescent and young adult cancer survivors become more active.

What’s involved?

Assessments

Complete before starting study and at 3 and 6 months:

  • 45-min online survey
  • Wear activity monitor 24/7 for 7 days
  • You will be compensated for assessment completion

Physical Activity Program

All Participants

  • Receive Fitbit, Opt2Move app, exercise prescription, 15-min orientation call
  • Track physical activity with Fitbit and use Opt2Move app daily
  • Additionally, you may receive 0-4 additional Opt2Move features focused on mindfulness and/or social support.

How can I learn more?

For questions: Phone: 312-503-3465; Email: O2M@nm.org

To complete online screening: https://redcap.link/O2M

Eligibility Criteria

Who can participate?

  • Adults (18-39) diagnosed with cancer (except non-melanoma skin cancer) at age 18-39
  • 5 years or less since cancer diagnosis
  • 3 months or more since completed primary treatment (i.e., surgery, chemotherapy, and/or radiation); may still be undergoing endocrine or hormonal therapies
  • Fluent in spoken and written English
  • Own a smartphone that is either an iPhone (version 5 or greater) or an Android (version 5.0 or greater)
  • Have internet access
  • Have no absolute contraindications to exercise (e.g., acute myocardial infarction, severe orthopedic conditions, or metastatic disease) OR willing to obtain medical clearance from a primary care physician if necessary
  • Engage in less than 60 minutes total each week of moderate to vigorous intensity physical activities such as walking, biking, or swimming
  • Willing to find a Buddy (someone who knows about your cancer and participation in this study and who is willing to participate by supporting you during the 6-month study)
Principal InvestigatorPhillips, Siobhan MPhillips, Siobhan M
ClinicalTrials.gov IdentifierNCT05375162IRB number STU00210628
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STELLAR

The STELLAR Program is a healthy lifestyle telehealth program designed for individuals who have been diagnosed with cancer, completed active treatment, and have 2 or 3 of the following health behaviors: 1) have a BMI of 25 or greater, 2) perform less than 90 minutes a week of moderate or …

The STELLAR Program is a healthy lifestyle telehealth program designed for individuals who have been diagnosed with cancer, completed active treatment, and have 2 or 3 of the following health behaviors: 1) have a BMI of 25 or greater, 2) perform less than 90 minutes a week of moderate or vigorous physical activity, 3) currently smoke.

Our central mission is to increase the accessibility of equitable health support and resources for cancer survivors within Northwestern Medicine’s network. Spanning over the course of 12 months, trial participants are randomly assigned to one of two distinct study arms. One arm involves telehealth sessions with a health promotionist, fostering a close and supportive partnership between participants and health coaches across a sequence of 16 remote sessions. The second arm offers a self-guided avenue, empowering participants with personalized tools for self-paced progress.

Eligibility Criteria
  • 18+ years old
  • Have 2 or 3 of the following: 1) BMI ≥ 25, 2) less than 150 minutes a week of moderate or vigorous physical activity, 3) currently smoke
  • A patient at Northwestern Medicine
  • Diagnosed with any cancer (except non-melanoma skin)​
  • Completed with curative-intent treatment
  • Alive and not opted out of research
  • Not pregnant​​​
  • No contraindications for exercise (heart attack in last year, pacemaker, etc.)
  • English or Spanish speaking​
  • Has an email address
Principal InvestigatorSpring, BonnieSpring, Bonnie
ClinicalTrials.gov IdentifierNCT05687604IRB number STU00217509
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